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Daliri, K., Seifi-Shalamzari, N., Saeida-Ardekani, M., Ekraminasab, S., Neamatzadeh, H. (2020). Application of Golden Nanoparticles against Streptococcus Mutans for Prevention of Caries Lesions. Shahid Sadoughi University of Medical Sciences- Journal Management System, 3(2), 56-61. doi: 10.18502/wjpn.v3i2.6155
Karim Daliri; Neda Seifi-Shalamzari; Maryam Saeida-Ardekani; Sedigheh Ekraminasab; Hossein Neamatzadeh. "Application of Golden Nanoparticles against Streptococcus Mutans for Prevention of Caries Lesions". Shahid Sadoughi University of Medical Sciences- Journal Management System, 3, 2, 2020, 56-61. doi: 10.18502/wjpn.v3i2.6155
Daliri, K., Seifi-Shalamzari, N., Saeida-Ardekani, M., Ekraminasab, S., Neamatzadeh, H. (2020). 'Application of Golden Nanoparticles against Streptococcus Mutans for Prevention of Caries Lesions', Shahid Sadoughi University of Medical Sciences- Journal Management System, 3(2), pp. 56-61. doi: 10.18502/wjpn.v3i2.6155
Daliri, K., Seifi-Shalamzari, N., Saeida-Ardekani, M., Ekraminasab, S., Neamatzadeh, H. Application of Golden Nanoparticles against Streptococcus Mutans for Prevention of Caries Lesions. Shahid Sadoughi University of Medical Sciences- Journal Management System, 2020; 3(2): 56-61. doi: 10.18502/wjpn.v3i2.6155

Application of Golden Nanoparticles against Streptococcus Mutans for Prevention of Caries Lesions

World Journal of Peri and Neonatology
Volume 3, Issue 2, December 2020, Pages 56-61    PDF (490.02 K)
Document Type: Original Article
DOI: 10.18502/wjpn.v3i2.6155
Authors
Karim Daliri1; Neda Seifi-Shalamzari* 2; Maryam Saeida-Ardekani3; Sedigheh Ekraminasab3; Hossein Neamatzadeh3, 4
1Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Emergency Medicine, Shahrekord University of Medical Science, Shahrekord, Iran
3Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4Department of Medical Genetics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract
Background: Dental caries also known as baby bottle tooth decay, is a critical public health problem around the world for which Streptococcus mutans (S.mutans) has been introduced as the main infectious etiology. In the past two decades, nanotechnology has permitted the development of new materials with antimicrobial properties. The aim of this study was to compare the bactericidal and bacteriostatic effects of three golden nanoparticles (SP, NR, and CS) on S.mutans.
Methods: To determine the minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs), a liquid dilution method was applied.
Results: All golden nanoparticles (GNPs) showed antimicrobial activity with no statistically significant differences (> 0.05) in MIC or MBC.
Conclusion: Our findings revealed that the size and shape of the nanoparticles did not significantly affect the antimicrobial properties of the GNPs. This finding might be useful for achieving important clinical effects with reduced toxicity in the management of early childhood caries in future in vivo studies.
Keywords
Dental caries; Nanoparticles; Streptococcus mutans; Antimicrobial; Fluoride
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