Statistics

Number of Journals8
Number of Issues54
Number of Articles392
Article View138,355
PDF Download97,198
Ekraminasab, S., Dadbinpour, E., Rafati, S., Dadbinpour, A., Ghasemi, F., Mazaheri, M. (2024). Maternal Risk Factors Associated with Congenital Abnormalities in Infants Born in Yazd from 2018 to 2021. Shahid Sadoughi University of Medical Sciences- Journal Management System, 6(2), 83-90. doi: 10.18502/wjpn.v6i2.15489
Sedigheh Ekraminasab; Elahe Dadbinpour; Shiva Rafati; Ali Dadbinpour; Fatemeh Ghasemi; Mahta Mazaheri. "Maternal Risk Factors Associated with Congenital Abnormalities in Infants Born in Yazd from 2018 to 2021". Shahid Sadoughi University of Medical Sciences- Journal Management System, 6, 2, 2024, 83-90. doi: 10.18502/wjpn.v6i2.15489
Ekraminasab, S., Dadbinpour, E., Rafati, S., Dadbinpour, A., Ghasemi, F., Mazaheri, M. (2024). 'Maternal Risk Factors Associated with Congenital Abnormalities in Infants Born in Yazd from 2018 to 2021', Shahid Sadoughi University of Medical Sciences- Journal Management System, 6(2), pp. 83-90. doi: 10.18502/wjpn.v6i2.15489
Ekraminasab, S., Dadbinpour, E., Rafati, S., Dadbinpour, A., Ghasemi, F., Mazaheri, M. Maternal Risk Factors Associated with Congenital Abnormalities in Infants Born in Yazd from 2018 to 2021. Shahid Sadoughi University of Medical Sciences- Journal Management System, 2024; 6(2): 83-90. doi: 10.18502/wjpn.v6i2.15489

Maternal Risk Factors Associated with Congenital Abnormalities in Infants Born in Yazd from 2018 to 2021

World Journal of Peri & Neonatology
Volume 6, Issue 2, June 2024, Pages 83-90    PDF (640.76 K)
Document Type: Original Article
DOI: 10.18502/wjpn.v6i2.15489
Authors
Sedigheh Ekraminasab1, 2; Elahe Dadbinpour3; Shiva Rafati3; Ali Dadbinpour4, 5; Fatemeh Ghasemi6; Mahta Mazaheri* 1, 4
1Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3Department of Medical Ethics and Pediatrics, Faculty of Medicine, Shahed University, Tehran, Iran
4Department of Medical Genetics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
5Genetic and Environmental Adventures Research Center, School of Abarkouh Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
6Department of Midwifery, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract
Background: Maternal factors like age, existing medical conditions, and exposure to medications/substances during pregnancy are crucial in the development of congenital anomalies. This study aims to investigate maternal risk factors associated with congenital anomalies in newborns in Yazd from 2018 to 2021.
Methods: This particular research entails a cross-sectional descriptive analysis where the data concerning all live births and their respective mothers from the years 2018 to 2021 in the hospitals situated in Yazd were culled from the database of the National Mother and Newborn Health Registration System affiliated with Shahid Sadoughi University of Medical Sciences.
Results: Over four years, approximately 122,098 mothers' information was recorded in the mother's information registration system. The outcomes about social factors indicated that 1.3% of mothers with limited educational background and 0.62% of educated mothers had newborns with abnormal conditions. The heightened occurrence of newborns with congenital anomalies among mothers with lower educational attainment in comparison to their educated counterparts was deemed statistically significant (P < 0.001). Moreover, mothers under the age of 19 exhibited a 1.2% frequency of abnormalities, a rate significantly surpassing that of other age brackets.
Conclusion: The discernment that very young mothers and those with limited education exhibit a higher frequency of abnormalities underscores the necessity for enhanced medical attention and awareness within these specific demographic segments. Nevertheless, further comprehensive inquiries regarding risk factors among mothers and high-risk cohorts are imperative.
Keywords
Congenital anomalies; Newborn; Maternal age; Risk factors
References
  1. Taye M, Afework M, Fantaye W, Diro E, Worku A. Congenital anomalies prevalence in Addis Ababa and the Amhara region, Ethiopia: A descriptive cross-sectional study. BMC Pediatr 2019; 19(1): 234.
  2. Mohseni F, Mohammad S, Mousavi H, Ahmadi A. Examining prevalence of fetal defects and related factors in neonates born and hospitalized in Kerman Reference Hospital : A 66-Month Study. Int J Pediatr 2021; 9(6): 13653-62.
  3. Dadbinpour E, Dadbinpour A, Ekraminasab S, Ghasemi F, Nikkhah H, Rafati S, et al. Incidence and Types of Congenital Anomalies in Newborns of Yazd Hospitals during Six Years (2016- 2021) Based on National Mother and Newborn Health Registration System. World J Peri Neonatol 2023; 6(1): 17-25.
  4. May P, de Vries MD, Marais A, Kalberg W, Buckley D, Hasken JM, et al. The prevalence of fetal alcohol spectrum disorders in rural communities in South Africa: A third regional sample of child characteristics and maternal risk factors. Alcohol Clin Exp Res 2022; 46(10): 1819-36.
  5. Abebe S, Gebru G, Amenu D, Mekonnen Z, Dube L. Risk factors associated with congenital anomalies among newborns in southwestern Ethiopia: A case-control study. PLoS One 2021; 16(1): e0245915.
  6. Lee KS, Choi YJ, Cho J, Lee H, Lee H, Park SJ, et al. Environmental and Genetic Risk Factors of Congenital Anomalies: an Umbrella Review of Systematic Reviews and Meta-Analyses. J Korean Med Sci 2021; 36(28): e183.
  7. Wills V, Abraham J, Sreedevi NS. Congenital anomalies: the spectrum of distribution and associated maternal risk factors in a tertiary teaching hospital. Obstetrics and Gynecology 2017; 6(4): 15552017.
  8. Fang N-W, Huang Y-S, Yin C-H, Chen J-S, Chiou Y. Maternal risk factors in offspring with congenital anomalies of the kidney and urinary tract in Asian women. Pediatr Nephrol 2023; 38(9): 3065-70.
  9. Shivanagappa M, Kumarachar SH, Mahadevaiah M, Mahesh M. Pattern of congenital anomalies and associated maternal risk factors : A study from Mysore, South India. Indian Journal of Obstetrics and Gynecology Research 2019; 6(4): 444-7.
  10. Hamid U, Bashir S, Jabeen F. Diagnosis of congenital anomalies, its demographic patterns and associated maternity risk factors among children hospitalized at Lal Ded Hospital, Srinagar. International Journal of Scientific and Research Publications 2022; 12(11): 229-33.
  11. DeSilva M, Munoz FM, Mcmillan M, Kawai AT, Marshall H, Macartney KK, et al. Congenital anomalies: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine 2016; 34(49): 6015-26.
  12. Shahmirzady PS, Esteghamati A, Sadough A, Sarvi F. The risk factors associated with congenital anomalies in newborns. Journal of Comprehensive Pediatrics 2020; 11(3): e90136.
  13. Feng Y, Yu D, Yang L, Da M, Wang Z, Lin Y, et al. Maternal lifestyle factors in pregnancy and congenital heart defects in offspring: review of the current evidence. Ital J Pediatr 2014; 40: 85.
  14. Dingemann C, Sonne M, Ure B, Bohnhorst B, von Kaisenberg C, Pirr S. Impact of maternal education on the outcome of newborns requiring surgery for congenital malformations. PLoS One 2019; 14(4): e0214967.
  15. Zhang X, Chen L, Wang X, Wang X, Jia M, Ni S, et al. Changes in maternal age and prevalence of congenital anomalies during the enactment of China’s universal two-child policy (2013-2017) in Zhejiang Province, China: An observational study. PLoS Med 2020; 17(2): e1003047.
  16. Ahn D, Kim J, Kang J, Kim Y, Kim K. Congenital anomalies and maternal age: A systematic review and meta‐analysis of observational studies. Acta Obstet Gynecol Scand 2022. 101(5): 484-98.
  17. Goetzinger KR, Shanks AL, Odibo AO, Macones GA, Cahill AG. Advanced maternal age and the risk of major congenital anomalies. Am J Perinatol 2016; 34(3): 217-22.
  18. Aslam J, Khurshid S, Rehman S, Zafar S, Aslam I, Gulbaz S. Frequency of Various Congenital Anomalies and Associated Maternal Risk Factors, an Experience at Tertiary Care Hospital. Pakistan Journal of Medical & Health Sciences 2023; 17(6): 215-7.
  19. Mazaheri M, Yavari M, Behravesh S, NikKhah H, Ekraminasab S. Prenatal screening using QF-PCR and karyotyping with an evaluation of short tandem repeats markers in the Iranian population. World J Peri Neonatol 2023; 6(1): 1-9.
  20. Farzan F, Dadbinpour A, Ekraminasab S, Fallahzadeh H MM. Positive predictive value of screening tests in the first and second trimester of pregnancy in the diagnosis of trisomy 21, 18, and 13 using amniocentesis. World J Peri Neonatol 2022; 5(2): 74-82.
  21. Koumi MA El, Banna EA Al LI. Pattern of congenital anomalies in newborn : a hospital-based study. Pediatr Rep 2013; 5(1): e5.
  22. Ameen SK, Alalaf SK, Shabila NP. Pattern of congenital anomalies at birth and their correlations with maternal characteristics in the maternity teaching hospital, Erbil city, Iraq. BMC Pregnancy Childbirth 2018; 18(1): 1-8.
  23. Kamal NM, Othman N. Incidence and types of congenital anomalies in newborns in sulaimaniyah city in Iraq. Acta Med Iran 2018; 56(12): 769-76.
  24. Rostamizadeh L, Bahavarnia SR, Gholami R. Alteration in incidence and pattern of congenital anomalies among newborns during one decade in Azarshahr, Northwest of Iran. Int J Epidemiol Res 2017; 4(1): 37-43.
  25. Khan A, Zuhaid M, Fayaz M, Ali F, Khan A, Ullah R, et al. Frequency of congenital anomalies in newborns and its relation to maternal health in a tertiary care hospital in Peshawar, Pakistan. Int J Med Stud 2014; 2(2): 37-40.
  26. Ye W, Luo C, Huang J, Li C, Liu Z, Liu F. Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis. BMJ 2022.
  27. Zhao E, Zhang Y, Zeng X, Liu B. Association between maternal diabetes mellitus and the risk of congenital malformations: A meta-analysis of cohort studies. Drug Discov Ther 2015; 377: e067946.
  28. Shengelia ND, Bespalova O, Shengelia MO. Maternal pregestational diabetes as an factor in the genesis of congenital malformations of the fetus. Journal of Obstetrics and Women's Diseases 2022; 71(3): 101-10.
  29. Askari M, Dadbinpour A, Ekraminasab S, Shukohifar M. Incidence and risk factors related to gestational diabetes mellitus among women in Yazd: a prospective cohort study. World J Peri Neonatol 2023; 5(2): 65-73.
  30. Lookzadeh MH, Alipour MR, Vakili-Zarch A, Ekraminasab S. Prevalence of congenital heart diseases in neonates of diabetic mothers: a cross sectional study in Yazd. World J Peri Neonatol 2022; 5(1): 24-9.
  31. Lookzadeh MH, Alipour MR, Vakili Zarch A ES. Prevalence of Hypertrophic Cardiomyopathy in Neonates of Diabetic Mothers: A Six-month Follow-up Study. World J Peri Neonatol 2022; 5(2): 58-64.
  32. Chen L-J, Chiu C-H, Huang J-Y, Chen P-J, Su P, Yang S-F, et al. Maternal diabetes mellitus and birth defects in Taiwan: A 5-year nationwide population-based cohort study. J Chin Med Assoc 2023; 86(6): 589-95.
  33. Parnell AS, Parnell AS, Correa A, Reece E. Pre-pregnancy obesity as a modifier of gestational diabetes and birth defects associations: a systematic review. Matern Child Health J 2017; 21(5): 1105-20.
 

 

 

Statistics
Article View: 226
PDF Download: 120


Journal Management System. Powered by Sinaweb