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Evaluation of the prevalence and prognosis of various types of premature ventricular contractions (PVCs) following catheter ablation in patients at afshar hospital, yazd, iran (2015–2020) | ||
| Cardiovascular Biomedicine | ||
| Volume 5, Issue 1, September 2025, Pages 45-51 PDF (467.73 K) | ||
| Document Type: original articles | ||
| DOI: 10.18502/cbj.v5i1.19451 | ||
| Authors | ||
| Ahmad Abdolrezaie Anari; Seyed Mostafa Seyed Hossaini Tezerjani; Mohammadtaghi Sarebanhassanabadi; Faezeh Dehghani Tafti; Parisa Peigan* ; Farnoosh Ghomi | ||
| 1. Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran | ||
| Abstract | ||
| Objectives: Premature ventricular contraction (PVC) is a common cardiac arrhythmia characterized by heartbeats originating from the ventricles rather than the sinoatrial node. Although radiofrequency catheter ablation (RFCA) is a preferred treatment, its efficacy and prognostic impact remain incompletely established, particularly in developing countries where cardiovascular diseases are a leading cause of mortality. This study aims to investigate the prevalence and predictive outcomes of different PVC types following ablation therapy. Methods: A retrospective, cross-sectional study was performed on all patients who underwent premature ventricular contraction (PVC) ablation at the Catheterization Laboratory of Afshar Hospital in Yazd, Iran, from 2015 to 2020. Patient data were collected using a census sampling approach, based on medical records, with PVC diagnoses confirmed by an electrophysiology specialist. The study examined demographic characteristics, PVC morphology based on surface electrocardiograms (ECGs), and the anatomical origin identified through electrophysiological mapping. Ablation success was defined as a reduction of ≥80% in PVC burden, while recurrence was defined as more than 10% PVCs on a 24-hour Holter monitor during follow-up. Data were analyzed using SPSS software. Results: The study included 75 patients (56% male, 44% female) with a mean age of 47.0 ± 13.7 years. The most common site of PVC origin was the right ventricular outflow tract (RVOT), found in 54.7% of cases. Common comorbidities included hypertension (31%) and diabetes mellitus (11%). Palpitations were the most frequently reported symptom, seen in 63% of patients. The overall success rate of ablation was 81.3%. Complications were rare and included catheter site hematoma (2.7%) and thromboembolism (1.3%). Among patients who had successful ablation, 18% experienced recurrence. A statistically significant relationship was found between the anatomical origin of PVC and ablation success (p < 0.0001). However, the origin of PVCs was not significantly associated with recurrence or the timing of recurrence (p > 0.08). Conclusions: This study identifies palpitations as the primary symptom in patients with premature ventricular contractions (PVCs), which most commonly originate from the ventricular outflow tracts. Hypertension and diabetes mellitus were identified as significant comorbidities. Radiofrequency ablation demonstrated a high success rate, with few complications and a low recurrence rate. Notably, the anatomical origin of PVCs was a substantial predictor of ablation success. | ||
| Keywords | ||
| Arrhythmia; PVC; Ablation; RFCA | ||
| References | ||
|
1.Kasper D, Fauci A, Hauser S, et al. Harrison's principles of internal medicine, 19e. New York, NY, USA: McGraw-Hill.2015.
2.Cecil RLF, Goldman L, Schafer AI. Goldman's Cecil Medicine, Expert Consult Premium Edition--Enhanced Online Features and Print, Single Volume, 24: Goldman's Cecil Medicine. Elsevier Health Sciences. 2012.
3.Yang X, Jin XY, Shen JF. A PVC identification method of the ECG signal based on an improved BPNN. Applied Mechanics and Materials. 2015;738:578-581.
4.Chikh MA, Ammar M, Marouf R. A neuro-fuzzy identification of ECG beats. JMed Syst. 2012;36(2):903-14.
5.Nathani P, Shetty S, Lokhandwala Y. Ventricular tachycardia in structurally normal hearts: recognition and management. J Assoc Physicians India. 2007;55:33-8.
6.Kuck Kh, Kunze Kp, Schlüter M, et al. Ablation of a left-sided free-wall accessory pathway by percutaneous catheter application of radiofrequency current in a patient with the Wolff -Parkinson -White syndrome. Pacing Clin Electrophysiol. 0989;12(10): 1681-90.
7.Kim SS, Knight BP. Long-term risk of Wolff-Parkinson-White pattern and syndrome. Trends Cardiovasc Med. 2017;27 (4):260-268.
8.Liu A, Pusalkar P. Asymptomatic Wolff–Parkinson–White syndrome: incidental ECG diagnosis and a review of literature regarding current treatment. BMJ Case Rep. 2011; 2011:bcr0520114192.
9.Priori SG, Blomström-Lundqvist C, Mazzanti A, et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC) Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). Europace. 2015;17(11):1601-87.
10.Pedersen CT, Kay GN, Kalman J, et al. EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Europace. 2014;16(9):1257-83.
11.Lin D, Ilkhanoff L, Gerstenfeld E, et al. Twelve-lead electrocardiographic characteristics of the aortic cusp region guided by intracardiac echocardiography and electroanatomic mapping. Heart Rhythm. 2008;5(5):663-9.
12.Lee AK, Andrade J, Hawkins NM, et al. Outcomes of untreated frequent premature ventricular complexes with normal left ventricular function. Heart. 2019;105(18):1408 -1413.
13.Chen Y, Wu S, Li W, et al. Gender-Related Association of Serum Uric Acid Levels with Premature Ventricular Contraction. Int Heart J. 2018;59(6):1246-1252.
14.Sarrazin J-F, Labounty T, Kuhne M, et al. Impact of radiofrequency ablation of frequent post-infarction premature ventricular complexes on left ventricular ejection fraction. Heart Rhythm. 2009;6(11):1543-9.
15.Zang M, Zhang T, Mao J, et al. Beneficial effects of catheter ablation of frequent premature ventricular complexes on left ventricular function. Heart. 2014;100(10):78 7-93.
16.Bogun F, Crawford T, Chalfoun N, et al. Relationship of frequent postinfarction premature ventricular complexes to the reentry circuit of scar-related ventricular tachycardia. Heart Rhythm. 2008;5(3):367-74.
17.Van Malderen S, Wijchers S, Akca F, et al. Mismatch between the origin of premature ventricular complexes and the noncompacted myocardium in patients with noncompaction cardiomyopathy: involvement of the conduction system? Ann Noninvasive Electrocardiol. 2017;22(2):e12394.
18. Tanaka A, Takemoto M, Masumoto A, et al. Radiofrequency catheter ablation of premature ventricular contractions from near the His bundle. J Arrhythm. 2019;35(2): 252-261. | ||
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