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Sakhaei, R., Mohsenpour, M. (2020). Low Glycemic Load or Index Diet in Association with Acne Vulgaris: A Systematic Review and Meta-analysis. Shahid Sadoughi University of Medical Sciences- Journal Management System, 1(1), -. doi: 10.18502/ccb.v1i1.2869
Roya Sakhaei; Mohammad Ali Mohsenpour. "Low Glycemic Load or Index Diet in Association with Acne Vulgaris: A Systematic Review and Meta-analysis". Shahid Sadoughi University of Medical Sciences- Journal Management System, 1, 1, 2020, -. doi: 10.18502/ccb.v1i1.2869
Sakhaei, R., Mohsenpour, M. (2020). 'Low Glycemic Load or Index Diet in Association with Acne Vulgaris: A Systematic Review and Meta-analysis', Shahid Sadoughi University of Medical Sciences- Journal Management System, 1(1), pp. -. doi: 10.18502/ccb.v1i1.2869
Sakhaei, R., Mohsenpour, M. Low Glycemic Load or Index Diet in Association with Acne Vulgaris: A Systematic Review and Meta-analysis. Shahid Sadoughi University of Medical Sciences- Journal Management System, 2020; 1(1): -. doi: 10.18502/ccb.v1i1.2869

Low Glycemic Load or Index Diet in Association with Acne Vulgaris: A Systematic Review and Meta-analysis

Critical Comments in Biomedicine
Volume 1, Issue 1, March 2020    PDF (2.97 M)
Document Type: Article
DOI: 10.18502/ccb.v1i1.2869
Authors
Roya Sakhaei1; Mohammad Ali Mohsenpour* 2
1Nutrition and Food Security Research Center, Department of Nutrition, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2Nutrition and Food Security Research Center, Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract
Background: Social life can be affected by skin condition. Acne Vulgaris (AV) is a multi-factorial skin disorder that affects many people. Several dietary factors are associated with AV.
Objectives: Different findings on glycemic indices led us to investigate the effect of the dietary glycemic index (GI) and glycemic load (GL) on AV by a systematic review and meta-analysis.
Methods: Observational studies and clinical trials were extracted from PubMed, EMBASE, Scopus, and Google Scholar. The mean ± Standard division (SD) for acne grading in clinical trials and the mean ± SD GI or GL of the diet for observational studies were used for meta-analysis.
Results: We found that nine out of 15 studies were eligible for systematic review clinical trials (N = 3) and observational studies (N = 6) designs. The meta-analysis of three studies clinically assessed the effect of GI/GL on acne and showed that a diet with lower GI/GL reduced the acne severity (Hedges’g = -0.91, 95% CI: -1.57, -0.25, P = 0.007). The analysis of six observational studies showed that dietary habit with higher GI might not affect the acne severity in patients with AV (Hedges’g = 0.07, 95%CI: -0.23, 0.38, P = 0.636), but individuals with higher acne severity had a diet with higher GL (Hedges’g = 0.64, 95%CI: 0.01, 1.26, P = 0.045).
Conclusions: Diet, as a part of lifestyle, is associated with AV. Adherence to lower GL diet may reduce the severity of AV. Further well-designed clinical trials are required to confirm these results.
Keywords
Acne Vulgaris; Glycemic Index; Glycemic Load; Diet
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