Andishmand, Abbas, Montazer Ghaem, Hossein, Fallahzadeh, Somayeh, Andishmand, Mojtaba, Haghaninejad, Hasan, Dehghani Tafti, Faezeh, Namayandeh, Seyedeh Mahdieh, Nough, Hossein (2024). Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran. Shahid Sadoughi University of Medical Sciences- Journal Management System, 4(1), 1-9. doi: 10.18502/cbj.v4i1.16221
Abbas Andishmand; Hossein Montazer Ghaem; Somayeh Fallahzadeh; Mojtaba Andishmand; Hasan Haghaninejad; Faezeh Dehghani Tafti; Seyedeh Mahdieh Namayandeh; Hossein Nough. "Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran". Shahid Sadoughi University of Medical Sciences- Journal Management System, 4, 1, 2024, 1-9. doi: 10.18502/cbj.v4i1.16221
Andishmand, Abbas, Montazer Ghaem, Hossein, Fallahzadeh, Somayeh, Andishmand, Mojtaba, Haghaninejad, Hasan, Dehghani Tafti, Faezeh, Namayandeh, Seyedeh Mahdieh, Nough, Hossein (2024). 'Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran', Shahid Sadoughi University of Medical Sciences- Journal Management System, 4(1), pp. 1-9. doi: 10.18502/cbj.v4i1.16221
Andishmand, Abbas, Montazer Ghaem, Hossein, Fallahzadeh, Somayeh, Andishmand, Mojtaba, Haghaninejad, Hasan, Dehghani Tafti, Faezeh, Namayandeh, Seyedeh Mahdieh, Nough, Hossein Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran. Shahid Sadoughi University of Medical Sciences- Journal Management System, 2024; 4(1): 1-9. doi: 10.18502/cbj.v4i1.16221

Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran

Cardiovascular Biomedicine
Volume 4, Issue 1, August 2024, Pages 1-9    PDF (775.01 K)
Document Type: Original articles
DOI: 10.18502/cbj.v4i1.16221
Authors
Abbas Andishmand1; Hossein Montazer Ghaem* 2; Somayeh Fallahzadeh3; Mojtaba Andishmand1; Hasan Haghaninejad1; Faezeh Dehghani Tafti1; Seyedeh Mahdieh Namayandeh1; Hossein Nough1
1Yazd Cardiovascular Research Center, Non- communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2Cardiovascular Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
3khatamolanbia Hospital, Abarkooh University of Medical Sciences,Yazd, Iran
Abstract
Objectives: Percutaneous Trans-Mitral Commissurotomy (PTMC) is an effective non-surgical treatment in patients with severe rheumatic mitral valve stenosis. This study aimed to evaluate the mid-term results of this procedure in central Iran.
 
Methods: This retrospective study was performed on 101 patients with severe mitral valve stenosis who underwent successful PTMC from March 2011 to September 2018 in Afshar Hospital in Yazd. At follow-up, all patients underwent clinical examination, two-dimensional and color Doppler echocardiography, and events were recorded. Data were analyzed using SPSS software version 19.
 
Results: The mean age of the patients was 44.79± 11.72 years, and 83.3% were female. The mean follow-up time was 38.98 23.33 months (6-94 months).25.8% had AF rhythm, and 12% had previous PTMC or OMVC or CMVC. After percutaneous Trans-Mitral Commissurotomy, 97% of patients were in NYHA functional class I, II and the mitral valve area (MVA) increased from 0.92 ± 0.18 to 1.66± 0.29 cm2 (p<0.0001). Pulmonary artery systolic pressure decreased from 46.96± 18.56 mmHg to 38.43±14.02 mmHg (p<0.0001). The Mean mitral valve gradient decreased from 12.37± 3.99 mmHg to 4.79± 2.38 mmHg (p<0.0001). Restenosis rate and severe mitral regurgitation resulting in mitral valve replacement (MVR) were 10.9% and 2%, respectively. Two patients died because of intracranial hemorrhage (ICH). During the follow-up event, free survival was 82.2%. Multivariable analysis revealed that the predictors of shorter event-free survival were AF rhythm (HR; 4.5, 95%CI;1.59-12.9, P=0.005) and post PTMC higher NYHA functional class (HR;2.2, CI;1-4.8,p=0.049).
 
Conclusions: Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central Iran are the same as in other parts of the world. This procedure is an effective and low-risk treatment for severe mitral valve stenosis.
Keywords
Survival; Rheumatic fever; mitral valve stenosis; percutaneous trans-mitral commissurotomy
References
Statistics
Article View: 275
PDF Download: 185