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The effect of Citrus aurantifolia (Christm) Swingle on epistaxis as a pre-hospital treatment | ||
| Advances in Pharmacology and Therapeutics Journal | ||
| Volume 5, Issue 1 - Serial Number 8, March 2025, Pages 13-19 PDF (934.55 K) | ||
| Document Type: Original Article | ||
| DOI: 10.18502/aptj.v5i1.18131 | ||
| Authors | ||
| Faeze Zeinali* ; fatemeh modjallal; soheila Azimi Abarghouei; Mohamadali jafari; Majid hajimaghsoudi; Behzad Zeinaly | ||
| Abstract | ||
| Objective: Epistaxis is a frequent complaint of emergency ward patients. This study investigated the local effect of Citrus aurantifolia (Christm) Swingle (wfo-0001242548). Juice on the control of spontaneous epistaxis in emergency ward patients. Materials and Methods: This single-blind clinical trial was carried out on 150 patients with epistaxis that referred to the emergency ward. They were randomly assigned into two groups of 75 patients. Cotton soaked in lidocaine and then phenylephrine was used for the control group. Also, cotton soaked in lidocaine and Citrus aurantifolia juice was used intra-nasally for the intervention group. The epistaxis control rate was measured. Results: The epistaxis control rate was 84% in the control group and 37.3% in the intervention group 10 min after the treatment in two groups. The recurrence rate of epistaxis 24 h of follow-up was 14.7% in the control group and 13.3% in the intervention group (P>0.05). Also, the complications observed in patients in the two groups were not significantly different. Aggravation of epistaxis, allergy, pain, and burning sensation was present in 6.7%, 4%, and 10.7% of patients in the control group and in 5.3%, 6.7%, and 16% of patients in the intervention group. Conclusion: The present study suggested that Citrus aurantifolia has a mild effect in the treatment of epistaxis, but it was not as effective as phenylephrine in controlling epistaxis; nevertheless, in the first time of epistaxis and mild items, it can be used as an available method at home. | ||
| Keywords | ||
| Epistaxis; Phenylephrine; Citrus aurantifolia (Christm) Swingle, Iranian Traditional Medicine | ||
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