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Hasheminasab, H., Yavari, M., Kazemi, M. (2019). Assessment of the Frequency and Molecular Identity of Mycoplasma Species in Women with a History of Idiopathic Recurrent Abortion: A Case Control Study. Shahid Sadoughi University of Medical Sciences- Journal Management System, 2(2), 54-60. doi: 10.18502/wjpn.v2i2.4339
Hamid Hasheminasab; Mahdieh Yavari; Mohammad Javad Kazemi. "Assessment of the Frequency and Molecular Identity of Mycoplasma Species in Women with a History of Idiopathic Recurrent Abortion: A Case Control Study". Shahid Sadoughi University of Medical Sciences- Journal Management System, 2, 2, 2019, 54-60. doi: 10.18502/wjpn.v2i2.4339
Hasheminasab, H., Yavari, M., Kazemi, M. (2019). 'Assessment of the Frequency and Molecular Identity of Mycoplasma Species in Women with a History of Idiopathic Recurrent Abortion: A Case Control Study', Shahid Sadoughi University of Medical Sciences- Journal Management System, 2(2), pp. 54-60. doi: 10.18502/wjpn.v2i2.4339
Hasheminasab, H., Yavari, M., Kazemi, M. Assessment of the Frequency and Molecular Identity of Mycoplasma Species in Women with a History of Idiopathic Recurrent Abortion: A Case Control Study. Shahid Sadoughi University of Medical Sciences- Journal Management System, 2019; 2(2): 54-60. doi: 10.18502/wjpn.v2i2.4339

Assessment of the Frequency and Molecular Identity of Mycoplasma Species in Women with a History of Idiopathic Recurrent Abortion: A Case Control Study

World Journal of Peri and Neonatology
Volume 2, Issue 2, October 2019, Pages 54-60    PDF (673.31 K)
Document Type: Original Article
DOI: 10.18502/wjpn.v2i2.4339
Authors
Hamid Hasheminasab1; Mahdieh Yavari2; Mohammad Javad Kazemi* 3
1Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Yazd, Iran
2Department of Biology, Faculty of Science, Yazd University, Yazd, Iran
3Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Yazd, Iran
Abstract
Background: Abortion is the most common complication in the first trimester of pregnancy. Infections are reported as the etiology of abortions. Some species of Mycoplasmas are seen in the lower genital tract. The aim of this study was to investigate the frequency and the molecular identity of Mycoplasma species in women with a history of idiopathic recurrent abortion.
Methods: This study was carried out on 68 women with a history of recurrent abortion. Detecting 16S rRNA to identify the infection of Mycoplasma was done by polymerase chain reaction (PCR) on cervical samples. Furthermore, the sequencing of positive samples was performed to identify the species of Mycoplasma.
Results: The results showed that only one woman with history of three times abortions was infected by Mycoplasma. Her gestational age was six weeks and she had apparent signs of infection. After sequencing, Mycoplasma genitalium was diagnosed as the infectious agent. The prevalence rate of Mycoplasma was 1.47% and 0% in the case and control groups, respectively. There was no significant association betweenabortion and Mycoplasma infection.
Conclusion: It seems more studies are necessary to evaluate the relationship between Mycoplasma infection and abortion. Moreover the increase in the level of public health due to better education and the improvement of contraceptive methods compared to the past has created a significant reduction in Mycoplasma infection.
Keywords
Recurrent Abortion; Miscarriage; Mycoplasma; 16S rRNA
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